Nijhout HF, Grunert LW. The cellular and physiological mechanism of wing-body scaling in Manduca sexta.. Science 330: 1693-1695 (2010).
Tobler A, Nijhout HF. Developmental constraints on the evolution of wing-body allometry in Manduca sexta. Evolution & Development 12: 57-66 (2010).
Nijhout HF. Molecular and physiological basis of colour pattern formation. Advances in Insect Physiology. 38: 219-265 (2010).
Best J, Nijhout HF, Reed M. Serotonin synthesis, release and reuptake in terminals: a mathematical model. Theoretical Biology and Medical Modelling. 7: 34ff (2010)
Reed MC, Lieb A, Nijhout HF. The biological significance of substrate inhibition: A mechanism with diverse functions. BioEssays 32: 422-429 (2010).
Tobler A, Nijhout HF. A switch in the control of growth of the wing imaginal disks of Manduca sexta. PLoS-One 5(5): e10723 (2010).
Best J, Reed M, Nijhout HF. Models of dopaminergic and serotonergic signaling. Pharmacopsychiatry 43: S61-S66 (2010).
Diamond SE, Hawkins SD, Nijhout HF, Kingsolver, JG. Evolutionary divergence of field and laboratory populations of Manduca sexta in response to host-plant quality. Ecological Entomology 35: 166-174 (2010).
Nijhout HF, Roff DA, Davidowitz G. Conflicting processes in the evolution of body size and development time. Philosophical Transactions of the Royal Society B-Biological Sciences. 365: 567-575 (2010).
Bowsher JH, Nijhout HF. Partial co-option of the appendage patterning pathway in the development of abdominal appendages in the sepsid fly Themira biloba. Development Genes and Evolution 219: 577-587 (2010).
Thomas DC, Conti DV, Baurley J, Nijhout HF, Reed MC, and Ulrich CM. Use of pathway information in molecular epidemiology. Human Genomics 4: 21-42 (2009).
Nijhout HF, Gregory JF, Fitzpatrick C1, Cho E, Lamers KY, Ulrich CM, Reed MC. A mathematical model gives insights into the effects of vitamin B-6 deficiency on 1-carbon and glutathione metabolism. Journal of Nutrition 139: 784-791 (2009).
Howell AS, Savage NS, Johnson SA, Bose I, Wagner AW, Zyla TR, Nijhout HF, Reed MC, Goryachev AB and Lew DJ. Singularity in polarization: Rewiring yeast cells to make two buds. Cell 139: 731-743 (2009).
Nijhout HF and Suzuki, Y. Environment and genetic accommodation. Biological Theory 3:1-9 (2009).
Best JA, Nijhout HF, Reed MC. Homeostatic mechanisms in dopamine synthesis and release: a mathematical model. Theoretical Biology and Medical Modelling 6:21 (2009).
Reed M, Best J, Nijhout HF. Passive and active stabilization of dopamine in the striatum. Bioscience Hypotheses 2: 240-244 (2009).
Suzuki Y, Nijhout HF. Constraint and developmental dissociation of phenotypic integration in a genetically accommodated trait. Evolution & Development 10: 690-699 (2008).
Nijhout, HF. Size matters (but so does time), and It’s OK to be different. Developmental Cell 15: 491-492 (2008).
Nijhout HF, Reed M, Ulrich C. Mathematical models of one-carbon metabolism. Vitamins and Hormones 79: 45-82 (2008).
Ulrich CM, Reed MC, Nijhout HF. Modeling folate, one-carbon metabolism, and DNA methylation. Nutrition Reviews 8: S27-S30 (2008).
Ulrich CM, Neuhouser M, Liu A, Boynton A, Gregory JF, Shane B, James SJ, Reed MC, Nijhout HF. Mathematical modeling of folate metabolism: Predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis. Cancer Epidemiology Biomarkers & Prevention 17: 1822-1831 (2008).
Reed MC, Thomas R, Pavisic J, Nijhout HF, James SJ, Ulrich CM. A mathematical model of glutathione metabolism. Theoretical Biology and Medical Modelling 5(8): doi:10.1186/1742-4682-5-8 (2008).
Nijhout, HF. Developmental phenotypic landscapes. Evolutionary Biology 35: 100-103 (2008).
Suzuki Y, Nijhout HF. Genetic basis of adaptive evolution of a polyphenism by genetic accommodation. Journal of Evolutionary Biology 21: 57-66 (2008).
Nijhout HF, Reed MC. A mathematical model for the regulation of juvenile hormone titers. J. Insect Physiology 54: 255-264 (2008).
Leduc, D., Escartin, F., Nijhout, HF., Reed, MC., Liebl, U., Skouloubris, S. and Myllykallio, H. Flavin-dependent thymidylate synthase ThyX activity: Implications for the folate cycle in bacteria. J. Bacteriol. 189: 8537-8545 (2007).
Reed RD, Chen PH, and Nijhout, HF. Cryptic variation in butterfly eyespot development: the importance of sample size in gene expression studies. Evolution & Development 9: 2-9 (2007).
Nijhout, HF, Smith, WA. Schachar, I, Subramanian, S., Tobler, A. and Grunert, LW. The control of growth and differentiation of the wing imaginal disks of Manduca sexta. Developmental. Biology 302: 569-576 (2007).
Shingleton, A.W., Frankino, W.A., Flatt, T., Nijhout, H.F. and Emlen, D.J. Size and shape: the developmental regulation of static allometry in insects. BioEssays 29: 536-548 (2007).
Brandon, RN. and Nijhout, HF. The empirical non-equivalence of genic and genotypic models of selection: A decisive refutation of genic selectionism and pluralistic genic selectionism. Philosophy of Science 73: 277-297 (2007).
Bowsher, JH. and Nijhout, HF. Evolution of novel abdominal appendages in a sepsid fly from histoblasts, not imaginal discs. Evolution & Development 9: 347-354 (2007).
Anderson, D., Mattingly, J., Nijhout, HF., and Reed, MC. Propagation of fluctuations in biochemical systems, I. Linear SSC networks. Bull. Math. Biol. 69: 1791-1813 (2007).
Nijhout, HF., Reed, MC. and Ulrich, CM. A day in the life of cell metabolism. Biological Theory 2(2): 124-127. (2007).
Suzuki, Y. and Nijhout, HF. Evolution of a polyphenism by genetic accommodation. Science, 311: 650-652 (2006).
Nijhout, HF., Reed, MC., Anderson, D., Mattingly, J., James, SJ., and Ulrich, CM. Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation rate. Epigenetics. 1: 81-87 (2006).
Boyles, A.L. Billups, A.V., Deak, K.L., Siegel, D.G., Mehltretter, L., Slifer, S.H. Bassuk, A.G., Kessler, J.A., Reed, M.C. Nijhout, H.F. George, T.M., Enterline, D.S., Gilbert, J.R., Speer, M.C., and the NTD Collaborative Group. Neural tube defects and folate pathway genes: family-based association tests of gene–gene and gene–environment interactions. Environ. Health Perspect. 114: 1547-1552 (2006).
Reed, M.C., Nijhout, H.F., Neuhouser, M.L., Gregory J.F. III., Shane, B., James, S.J., Boynton, A. and Ulrich, C.M. A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. J. Nutr. 136: 2653-2661 (2006).
Ulrich , C.M., Nijhout , H.F. and Reed, M.C. Mathematical modeling: epidemiology meets systems biology. Cancer Epidemiol. Biomarkers Prev. 15: 827-829 (2006).
Veitia, R. and Nijhout, H.F. The robustness of the transcriptional response to alterations in morphogenetic gradients. BioEssays 28: 282-289 (2006).
Nijhout, H.F., Davidowitz, G. and Roff, D.A. A quantitative analysis of the mechanism that controls body size in Manduca sexta. Journal of Biology 5: 1-16 (2006).
Nijhout,HF. Stochastic gene expression: dominance, thresholds and boundaries., in Dominance and Haploinsufficiency, edited by Veitia, R.A. (2006), pp. 61-75, Landes Press.
Nijhout HF, Reed MC, Lam S-L,Shane B, Gregory JF, and Ulrich CM. In silico experimentation with a model of hepatic mitochondrial folate metabolism. Theoretical Biology and Medical Modelling 3: 40ff (2006).
Davidowitz, G. Roff, D.A. and Nijhout, H.F. A physiological perspective on the response of body size and development time to simultaneous directional selection. Integrative and. Comparative Biology 45: 525-531 (2005).
Edgar BA, Nijhout,HF. Growth and cell cycle control in Drosophila. In: Cell Growth: Control of Cell Size, Cold Spring Harbor Monographs, edited by M.N. Hall, M.Raff and G. Thomas (2004), pp. 23-83, Cold Spring Harbor Laboratory Press.
Yang AS, Martin CH, Nijhout HF. Geographic variation of caste structure among ant populations. Current Biology 14: 514-519 (2004).
Moczek AP, Nijhout HF. Trade-offs during the development of primary and secondary sexual traits in a horned beetle. American Naturalist 163: 184-191 (2004).
Davidowitz G, D’Amico LJ, Nijhout HF. The effects of environmental variation on a mechanism that controls insect body size. Evolutionary Ecology Research 6: 49-62 (2004).
Nijhout HF, Reed MC, Budu P, and Ulrich CM. A mathematical model of the folate cycle: New insights into folate homeostasis. Journal of Biological Chemistry 279: 55008-55016 (2004).
Reed, M.C., Nijhout, H.F., Sparks, R. and Ulrich, CM. A mathematical model of the methionine cycle. J. Theoret. Biol. 226: 33-43 (2004).
Nijhout, H.F. and Davidowitz, G. Developmental perspectives on phenotypic plasticity, canalization, and fluctuating asymmetry. In: Developmental Instability: Causes and Consequences, edited by M. Polak (2003), pp. 3-13, MIT Press.
Nijhout, HF. Polymorphic mimicry in Papilio dardanus: mosaic dominance, big effects and origins. Evolution & Development 5: 579-592 (2003).
Nijhout, H.F., Maini, P.K., Madzvamuse, A., Wathen, A. and Sekimura, T. Pigmentation pattern formation in butterflies –Experiments and models. Comptes Rendus Biologies 328: 717-727 (2003).
Wheeler, D.E. and Nijhout, H.F. A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. BioEssays 25: 994-1001 (2003).
Nijhout, HF.On the association between genes and complex traits. J. Invest. Dermatol. 8: 162-163 (2003).
Nijhout, HF. The control of body size in insects. Developmental Biology 261: 1-9 (2003).
Nijhout, HF.The importance of context in genetics. American Scientist 91: 416-423 (2003).
Nijhout HF, Berg AM, and Gibson WT. A mechanistic study of evolvability using the mitogen activated protein kinase cascade. Evolution & Development 5: 281-294 (2003).
Moczek, A.P. and Nijhout, H.F. Rapid evolution of a polyphenic threshold. Evolution & Development 5: 259-268 (2003).
Nijhout, HF. The development and evolution of adaptive polyphenisms. Evolution & Development 5: 9-18 (2003).
Davidowitz, G., D’Amico. L.J. and Nijhout, H.F. Critical weight in the development of insect body size. Evolution & Development. 5: 188-197 (2003).
Nijhout, HF.The control of growth. Development 130: 5863-5867 (2003).
Nijhout, HF. Gradients, diffusion and genes in pattern formation, in Origination of Organismal Form, edited by G. Müller and S. Newman, (2003), MIT Press.
Koch, PB. and Nijhout, HF. The role of wing veins in colour pattern development in the butterfly Papilio xuthus (Lepidoptera: Papilionidae). European Journal of Entomology 99: 67-72 (2002).
Nijhout, HF.The nature of robustness in development. BioEssays. 24: 553-563 (2002).
Nijhout, HF. Genetic regulatory networks. In: Encyclopedia of Evolution. (2002), Oxford University Press.
Nijhout, H.F. and Grunert, L.W. Bombyxin is a growth factor for wing imaginal disks in Lepidoptera. Proc. Nat. Acad. Sci. 99: 15446-15450 (2002).
Nijhout, H.F. and Davidowitz G. Developmental perspectives on phenotypic plasticity, canalization, and fluctuating asymmetry. In: Developmental Instability: Causes and Consequences, edited by M. Polak (2002), Oxford University Press.
Moczek, AP and Nijhout, HF.Developmental mechanism of threshold evolution in a polyphenic beetle. Evolution & Development 4: 252-264 (2002).
Nijhout, HF. The ontogeny of phenotypes. In: Cycles of Contingency, pp.129-140, edited by S oyama, P Griffiths and R Gray (2001), MIT Press.
Moczek, AP and Nijhout, HF. A method for sexing third instar larvae of the genus Onthophagus Latreille (Coleoptera Scarabeidae). Coleopt. Bull. (2001).
Nijhout, HF. Origin of butterfly wing patterns. In: The Character Concept in Evolutionary Biology, pp.511-529, edited by GA Wagner (2001), Academic Press.
Gilchrist, MA and Nijhout, HF. Non-linear developmental processes as sources of dominance. Genetics 159: 423-432 (2001).
Shafiei, M, Moczek AP, and Nijhout HF. Food availability controls the onset of metamorphosis in the dung beetle Onthophagus taurus (Cleoptera: Scarabeidae). Physiol. Entomol. 26: 173-180 (2001).
Emlen, DJ and Nijhout, HF. Hormonal control of horn length dimorphism in Onthophagus taurus (Coleoptera: Scarabeidae): a second critical period of sensitivity to juvenile hormone. J. Insect Physiol. 47: 1045-1054 (2001).
Browder, MH, D’Amico LJ and Nijhout, HF. The role of low levels of juvenile hormone esterase in the metamorphosis of Manduca sexta. J. Insect Science 1(11): 1-5 (2001).
D’ Amico, LJ, Davidowitz, G. and Nijhout, HF. The developmental and physiological basis of body size evolution in an insect. Proc. Roy. Soc. London, B, 268: 1589-1593 (2001).
McDonald, AK and Nijhout, HF. The effect of environmental conditions on mating activity of the Buckeye butterfly, Precis coenia. J. Res. Lepidopt. 35: 22-28 (2000).
Emlen, DJ and Nijhout, HF. The development and evolution of exaggerated morphologies in insects. Annual Review of Entomology 45: 661-708 (2000).
Miner, AL, Rosenberg, AJ and Nijhout, HF. Control of growth and differentiation of the wing imaginal disks of Precis coenia (Lepidoptera: Nymphalidae). J. Insect Physiol.. 46: 251-258 (2000).